Sunday, October 19, 2025
Ozempic and other GLP-1 drugs
Sunday, September 21, 2025
Jimmy Kimmel in NYT's: How Outrage at Kimmel Grew to a Shout From a Whisper
Right-wing users on social media on Tuesday were frustrated but not yet apoplectic about Jimmy Kimmel’s monologue. Things changed.
The Algorithms were manipulated to destroy Kimmel. Similar to the Rohingyas of Myanmar who suffered a genocide driven by Facebook alogorithms, according to Yuval Harari in his book Nexus.
"With algorithms increasingly curating the information we see, the power to control information becomes, in essence, the power to control the world. Harari asks readers to consider who controls these algorithms and who decides what information is amplified or lost in the noise. The decisions made by AI systems are not neutral, but they have real world consequences that shape our perceptions of reality."
"One of Harari's most chilling examples is the 2017 Rohingya massacre in Myanmar. This tragedy, fueled by AI algorithms on social media platforms, showed the dark side of information curation. Facebook's algorithms, designed to increase engagement by promoting emotionally charged content, contributed to the spread of hate speech. Harari highlights this as an example of AI's autonomy; while the goals may have been set by engineers, the algorithms made their own decisions on how to achieve these goals, with catastrophic consequences."
"In the digital age, where AI systems make decisions based on patterns, data, and probabilities, humans are no longer the sole actors in shaping information and reality. Instead, we are part of a complex web of interactions where machines play a central role in determining what we see, believe, and do. And Harari believes that this shift is deeply unsettling because it raises fundamental questions about autonomy, free will, and ethics. As such, Harari urges us to be mindful of what we are creating. The evolution of information is inevitable, but its consequences are still within our grasp. Nexus is a call to remember that in the sea of information, our humanity must remain our guiding light."
https://www.thedailystar.net/books-literature/news/unravelling-yuval-noah-hararis-nexus-3742871
Nexus is very well summarized here:
Yuval Noah Harari
Nexus: A Brief History of Information Networks from the Stone Age to AI
Nonfiction | Book | Adult | Published in 2024
https://www.supersummary.com/
“Mean tweets are great,” he wrote on X. “But they can be ignored. What can’t be ignored are your paying customers organizing against you and FCC investigations. That is exactly what we did.”
Stuart A. Thompson writes about how false and misleading information spreads online and how it affects people around the world. He focuses on misinformation, disinformation and other misleading content.
https://www.nytimes.com/2025/
Friday, September 19, 2025
Gary Kazparov on Autocrats
Dictators tend to lie about what they are doing. But they very often tell the truth about what they are planning to do.
- Gary Kazparov
Wednesday, September 17, 2025
“Find what you like and let it kill you.”
Kinky Friedman said, “Find what you like and let it kill you.”
The title of this piece, “Find What You Love, and Let It Kill You,” is taken from a popular quote misattributed to Charles Bukowski, the renowned German-American poet. In reality, the original quote belongs to the singer Kinky Friedman, with the word “like” instead of “love.”
Word on the net is, the quote came from one of Bukowski’s letters. It’s unverified and most likely fake, but I nevertheless find the words beautiful.
The letter goes like this:
“My dear,
Find what you love and let it kill you. Let it drain from you your all. Let it cling onto your back and weigh you down into eventual nothingness. Let it kill you, and let it devour your remains.
For all things will kill you, both slowly and fastly, but it’s much better to be killed by a lover.
Falsely yours, Henry Charles Bukowski.”
That “falsely yours” at the end says it all. This isn’t Bukowski, and whoever wrote it should’ve given themself some credit instead of stealing the poet’s name. Kudos for writing this piece, whoever you are, but shame for the misattribution.
Monday, September 15, 2025
New pill being tested to help the brain heal
This could be a game changer:
New pill being tested to help the brain heal
Ai Pro
A new pill is currently being tested in clinical trials to help the brain heal after injury or trauma. This pill works by promoting the growth of new brain cells and reducing inflammation in the brain, which can aid in the recovery process.
Early results from the trials are promising, with patients experiencing improvements in cognitive function, memory, and overall brain health. Researchers are hopeful that this pill could be a game-changer in the treatment of brain injuries and other neurological conditions.
If successful, this new pill could offer hope to the millions of people around the world who suffer from brain injuries and neurological disorders. Further research is ongoing, but the outlook is positive for this innovative new treatment.
Tuesday, September 9, 2025
Incarceration and Imagination:A symposium at Yale University
Self Care
"Take care of your body. It's the only place you have to live." — Jim Rohn
“You yourself, as much as anybody in the entire universe, deserve your love and affection.” — Buddha
“Self-care is how you take your power back.” — Lalah Delia
“Love yourself enough to set boundaries. Your time and energy are precious. You get to choose how you use it.” — Anna Taylor
“What lies behind us and what lies before us are tiny matters compared to what lies within us.” — Ralph Waldo Emerson
“Mindfulness isn’t difficult. We just need to remember to do it.” — Sharon Salzberg
“Doing nothing is sometimes the most productive thing.” — Paulo Coelho
“Your calm mind is the ultimate weapon against your challenges.” — Bryant McGill
“Owning our story and loving ourselves through that process is the bravest thing that we’ll ever do.” — Brené Brown
“Almost everything will work again if you unplug it for a few minutes… including you.” — Anne Lamott
“Take time off. The world will not fall apart without you.” — Malebo Sephodi
“Talk to yourself like someone you love.” — Brené Brown
“Talk to yourself like someone you love.” — Brené
“I celebrate myself, and sing myself.” — Walt Whitman
“And you? When will you begin that long journey into yourself?” — Rumi
“The bad news is time flies. The good news is you’re the pilot.” — Michael Altshuler
“Caring for myself is not self-indulgence, it is self-preservation, and that is an act of political warfare.” ― Audre Lorde
Monday, September 8, 2025
Quotes and Encouraging Words
SINCE LIVING WITH A CHRONIC ILLNESS LIKE MS IS LIKE LIVING IN A PRISON, THESE QUOTES CAN COMFORT THOSE PEOPLE AS WELL.
Jail Quotes and Encouraging Words for Someone in Prison
Being in jail or prison can be an incredibly isolating and challenging experience, often marked by feelings of despair, regret, or loneliness.
During these times, words of encouragement can serve as a powerful source of comfort and hope.
They remind individuals that change, growth, and a brighter future is always possible.
Supportive and uplifting words can provide the motivation needed to face struggles and work toward personal transformation.
Quotes offer a way to express understanding, compassion, and hope. These words remind inmates that their identity is not confined to their mistakes, and that growth, redemption, and second chances are always possible.
“Hate the sin, love the sinner.” – Mahatma Gandhi
“Every man is guilty of all the good he did not do.” – Voltaire
“The hardest prison to escape is your own mind.” – Bob Marley
“It is never too late to be what you might have been.” – George Eliot
“Every saint has a past, and every sinner has a future.” – Oscar Wilde
“No one saves us but ourselves. No one can, and no one may.” – Buddha
“He who has a why to live can bear almost any how.” – Friedrich Nietzsche
“Do what you can, with what you have, where you are.” – Theodore Roosevelt
“You are never too old to set another goal or to dream a new dream.” – C.S. Lewis
“Mistakes are always forgivable if one has the courage to admit them.” – Bruce Lee
“We must accept finite disappointment, but never lose infinite hope.” – Martin Luther King Jr.
“The only thing necessary for the triumph of evil is for good men to do nothing.” – Edmund Burke
“Your present circumstances don’t determine where you can go; they merely determine where you start.” – Nido Qubein
“What lies behind us and what lies before us are tiny matters compared to what lies within us.” – Ralph Waldo Emerson
Inspirational quotes for prisoners emphasize resilience, self-discovery, and the power of perseverance. They remind individuals that adversity can shape strength, that mistakes are stepping stones to growth, and that a brighter future is always within reach.
These words encourage prisoners to find purpose in their journey, and to believe in their ability to rise above current challenges with courage and determination.
“You are not defined by your worst moment.” – Bryan Stevenson
“Out of suffering have emerged the strongest souls.” – Khalil Gibran
“You only live once, but if you do it right, once is enough.” – Mae West
“It is in the darkest hour that we must focus to see the light.” – Aristotle
“It is not what happens to you, but how you react to it that matters.” – Epictetus
“There is no saint without a past, no sinner without a future.” – Augustine of Hippo
“Rock bottom became the solid foundation on which I rebuilt my life.” – J.K. Rowling
“Hardships often prepare ordinary people for an extraordinary destiny.” – C.S. Lewis
“Our greatest glory is not in never falling, but in rising every time we fall.” – Confucius
“Hope is being able to see that there is light despite all the darkness.” – Desmond Tutu
“Healing takes courage, and we all have courage, even if we have to dig a little to find it.” – Tori Amos
“Every adversity, every failure, every heartache carries with it the seed of an equal or greater benefit.” – Napoleon Hill
Sunday, September 7, 2025
Gemini expands on: Man’s life is brief and transitory, characterized by impermanence and the unpredictability of the future.
Expand on this statement:
Man’s life is brief and transitory, characterized by impermanence and the unpredictability of the future.
Life is often seen as a fleeting journey, a brief moment in the grand expanse of time. The statement, "Man’s life is brief and transitory, characterized by impermanence and the unpredictability of the future," speaks to this core human experience. It highlights the temporary nature of our existence and the lack of control we have over what lies ahead.
This idea has been a central theme in philosophy and literature for centuries. Thinkers from ancient Greece to modern times have grappled with the implications of our short time on Earth. The statement suggests that nothing in our lives is permanent—our physical bodies, our relationships, our worldly possessions. This can be a sobering thought, but it can also be a source of motivation.
Embracing this impermanence can lead to a greater appreciation for the present moment. If the future is unpredictable, and our time is short, then the only thing we truly have is the here and now. This can encourage us to live more fully, to pursue our passions, and to cherish the people in our lives.
The unpredictability of the future is also a key part of the statement. We can plan and prepare, but ultimately, we can't control what happens. A sudden illness, a career change, or an unexpected event can alter the course of our lives in an instant. This lack of control can be frightening, but it also allows for hope and possibility. The future is not set in stone, and every day brings a new chance for change and growth.
In essence, the statement is a reminder to embrace the fleeting nature of life, to find meaning in the present, and to face the future with both humility and courage.
Do you have anything more to add?
The Psychological and Cultural Dimensions
The statement that life is brief and impermanent is not just a philosophical observation; it's a fundamental truth that cultures and individuals have grappled with for centuries. How we respond to this fact says a lot about our values. While the statement itself is universal, the human reaction to it varies dramatically across different traditions and on a personal level.
In Western thought, the concept of "memento mori"—Latin for "remember you must die"—has long served as a powerful reminder of mortality. This idea often motivated people to live a virtuous life, as they believed their time was limited and their actions had eternal consequences. This perspective views life as a linear journey with a definite end, placing great emphasis on achieving a legacy or fulfilling a purpose before that end arrives. The brevity of life becomes a call to action.
In contrast, Eastern philosophies often embrace a more cyclical view of time and existence. The Japanese aesthetic of wabi-sabi is a beautiful example of this. It finds beauty in things that are imperfect, transient, and incomplete, such as a weathered piece of wood or a hand-thrown ceramic bowl with a unique crack. This philosophy teaches us to see the natural process of decay and aging not as a flaw, but as a part of an object's story. It is a peaceful acceptance of impermanence, rather than a fight against it.
On a personal level, the knowledge of our fleeting time can have a profound psychological impact. For some, it may lead to existential anxiety or a feeling of hopelessness. But for many, it can be a powerful catalyst for change and purpose. When we truly accept that our time is limited, we are forced to confront what matters most to us. The simple, everyday moments suddenly feel more precious, and the things that once seemed important, like material possessions or social status, can fade into the background. This is a core principle of mindfulness, a practice that helps us intentionally focus on the present moment as a way to find clarity and peace amid the unpredictability of life.
Considering these different perspectives, how do you think our awareness of life's brevity changes what we prioritize?
That's a great question. The idea of life's transience is a deep one, and there's a lot more to unpack beyond its immediate philosophical implications.
The Pursuit of Legacy
One of the most profound human reactions to our impermanence is the pursuit of legacy. Knowing that our individual lives will end, we are driven to create something that will outlast us. This is the impulse behind art, literature, scientific discovery, and the desire to leave the world a little better than we found it. We want our ideas and contributions to echo through time, creating a kind of immortality not for ourselves, but for our influence.
This drive to create a lasting impact is a powerful force that has shaped human civilization.
The Paradox of Permanence
We also seek to create a sense of permanence in a world of change. We do this through tradition, ritual, and institutions. Think of a family's annual holiday dinner, a religious ceremony that has been performed for centuries, or the consistent rules of a sports game. These are all attempts to defy transience by creating fixed points in time—moments we can return to and rely on. By participating in these rituals, we connect with those who came before us and build a stable foundation for those who will come after.
The Role of Memory
Our relationship with memory also serves as a powerful counterpoint to impermanence. While our physical lives are brief, our stories and experiences can be passed down. Think of a photograph, a cherished family story, or a historical record. These are all ways we attempt to hold on to moments and people, making them feel less temporary. Memory, both personal and collective, acts as a bridge across the generations, allowing us to connect with the past and influence the future.
Ultimately, the tension between our brief existence and our desire for permanence is a fundamental part of the human condition. It's what gives our choices weight and our relationships value.
*To highlight a real-world example of an artifact that embodies the concept of human knowledge and influence outlasting a single lifetime. It is a picture of the Rosetta Stone itself. It is a large, dark stone tablet, inscribed with three different scripts, and it is usually shown in a glass case, surrounded by visitors, in the British Museum in London.
Wednesday, May 7, 2025
85-Year-Old: "It Took Me 50+ Years To Learn What I'm About To Share With You" | James Hollis...
Friday, February 7, 2025
Self-Transformation Through Mindfulness | Dr. David Vago | TEDxNashville
The adaptive interactions between the mind, brain, and body are fundamental to mental health and are highly relevant in psychiatric settings. These interactions involve complex neurobiological and physiological components that work together to maintain homeostasis, respond to stress, and promote well-being. Below is an overview of the key components and their therapeutic relevance:
1. Neurobiological Components
a. Neural Circuits and Neurotransmitters
Prefrontal Cortex (PFC): Involved in executive functions, decision-making, and emotion regulation. Dysregulation is linked to psychiatric disorders like depression and anxiety.
Amygdala: Plays a key role in processing fear and emotional responses. Hyperactivity is associated with anxiety and PTSD.
Hippocampus: Critical for memory and contextual learning. Chronic stress can impair hippocampal function, contributing to mood disorders.
Neurotransmitters:
Serotonin: Regulates mood, sleep, and appetite. Targeted by SSRIs in depression.
Dopamine: Involved in reward, motivation, and pleasure. Dysregulation is implicated in addiction and schizophrenia.
GABA and Glutamate: Maintain excitatory-inhibitory balance. Imbalances are linked to anxiety and epilepsy.
b. Neuroplasticity
The brain's ability to reorganize itself by forming new neural connections. Neuroplasticity is central to learning, recovery from injury, and therapeutic interventions like cognitive-behavioral therapy (CBT).
c. Stress Response Systems
Hypothalamic-Pituitary-Adrenal (HPA) Axis: Regulates cortisol release in response to stress. Chronic activation can lead to psychiatric disorders like depression.
Autonomic Nervous System (ANS):
Sympathetic Nervous System (SNS): Activates the "fight or flight" response.
Parasympathetic Nervous System (PNS): Promotes "rest and digest" functions. Dysregulation of the ANS is linked to anxiety and PTSD.
2. Physiological Components
a. Immune System
Inflammation: Chronic inflammation is associated with depression and other psychiatric disorders. Cytokines can cross the blood-brain barrier and affect mood and cognition.
Psychoneuroimmunology: Studies the interaction between psychological processes, the nervous system, and the immune system.
b. Endocrine System
Hormones like cortisol, oxytocin, and thyroid hormones play significant roles in mood regulation and stress responses.
c. Gut-Brain Axis
The bidirectional communication between the gut microbiome and the brain. Dysbiosis (imbalance in gut bacteria) is linked to anxiety, depression, and autism spectrum disorders.
d. Cardiovascular and Respiratory Systems
Stress and anxiety can lead to increased heart rate and blood pressure, while relaxation techniques can activate the PNS and promote calmness.
3. Adaptive Mind-Brain-Body Interactions
Homeostasis: The body's ability to maintain stability despite external changes. Psychiatric disorders often involve disrupted homeostasis.
Allostasis: The process of achieving stability through physiological or behavioral change. Chronic allostatic load can lead to mental and physical health issues.
Interoception: The perception of internal bodily states. Poor interoceptive awareness is linked to anxiety and eating disorders.
4. Therapeutic Relevance in Psychiatric Settings
a. Pharmacological Interventions
Target neurotransmitter systems (e.g., SSRIs, antipsychotics) to restore balance and alleviate symptoms.
b. Psychotherapy
CBT: Helps rewire maladaptive neural circuits.
Mindfulness-Based Therapies: Enhance neuroplasticity and interoceptive awareness.
Exposure Therapy: Reduces amygdala hyperactivity in anxiety disorders.
c. Lifestyle Interventions
Exercise: Promotes neurogenesis and reduces inflammation.
Diet: Supports gut-brain axis health and reduces inflammation.
Sleep Hygiene: Essential for neuroplasticity and emotional regulation